340 W Girard Avenue, Philadelphia, PA 19123 - CMX-2 Zoned Mixed-Use Property in Prime Northern Liberties Location. Discover a rare opportunity to own a well-maintained, turnkey property in the heart of Northern Liberties with valuable CMX-2 zoning, offering live/work flexibility in one of Philadelphias most vibrant commercial corridors. Formerly utilized as an owner-occupied storefront with residential living above and behind, 340 W Girard Avenue is perfectly suited for a professional office, boutique retail, or service-based businesses such as medical, legal, consulting, or financial services with the option to continue residential occupancy or convert to full commercial use. This property is currently configured as a single-family home and has been meticulously upgraded throughout. It features hardwood flooring, a modern open-concept kitchen with granite countertops and a five-burner gas range, a commercial-grade hood and bar area, and updated mechanicals including a 200-amp electrical panel, newer roof (2021), and a high-efficiency mini-split HVAC system. The home includes two spacious bedrooms, two full bathrooms, and a flexible bonus room ideal for a private office or waiting room setup. Additional value-add elements include: Whole-home water filtration system, including reverse osmosis drinking water, New front-facing windows (2020) and energy-efficient improvements, Private rear yard ideal for tranquil outdoor space, Built-in trash storage area and low-maintenance exterior. Located at a high-visibility intersection on Girard Avenue, surrounded by both residential density and foot traffic, this property offers incredible signage potential and brand exposure. Steps from Liberty Lands Park, 2nd Street Festival, and within walking distance to Fishtown, Frankford Avenue, and the El (Market-Frankford Line), the accessibility and energy of the location cannot be overstated. Whether you're an entrepreneur seeking a live-work arrangement, a professional expanding into a vibrant neighborhood, or an investor looking for flexible use in a fast-growing corridor, this is an ideal asset in one of Philadelphias most dynamic real estate markets. Contact us today to schedule a private showing or to request zoning and floor plan details.